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image: Inner Ear Undertakers

Inner Ear Undertakers

By | September 1, 2015

Support cells in the inner ear respond differently to two drugs that kill hair cells.

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image: The Regenerators

The Regenerators

By | September 1, 2015

A molecular signature makes it possible to trace the details of hair cell replacement in the mammalian inner ear.

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image: Rethinking Lymphatic Development

Rethinking Lymphatic Development

By | August 1, 2015

Four studies identify alternative origins for cells of the developing lymphatic system, challenging the long-standing view that they all come from veins.

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image: New Immunity

New Immunity

By | June 1, 2015

A scaffolding protein forms the hub of a newly identified immune pathway in plants.

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image: Looking for Latent HIV

Looking for Latent HIV

By | May 1, 2015

Sequencing HIV integration sites suggests that clonally expanded T-cell populations may not be the main source of latent virus.

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image: Soluble Signal

Soluble Signal

By | May 1, 2015

An immune protein previously thought to mark inactive T cells has a free-floating form that correlates with HIV disease progression.

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Growth Hormone Guidance

Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.

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