The Literature

» cell & molecular biology, immunology and cancer

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Growth Hormone Guidance

Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.

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image: Long Live Collagen

Long Live Collagen

By | March 1, 2015

Increased collagen expression is a common feature of many different pathways to extended longevity in worms.

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image: B Cell Bosses

B Cell Bosses

By | February 1, 2015

Gut bacteria in mice spur regulatory B cells to differentiate and release an anti-inflammatory cytokine.

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image: Cadherin Connection

Cadherin Connection

By | December 1, 2014

A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells.

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image: Mitochondria Munchers

Mitochondria Munchers

By | November 1, 2014

Glial cells consume mitochondria released by neurons in the optic nerve.

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image: Cone Cell Correctors

Cone Cell Correctors

By | October 1, 2014

In mice, adult cone cell outer segments and their visual functions deteriorate if two microRNAs are not present.

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image: Beneficial Brew

Beneficial Brew

By | June 1, 2014

Drinking green tea appears to boost the activity of DNA repair enzymes.

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image: Long-Distance Call

Long-Distance Call

By | May 1, 2014

Neurons may use interferon signals transmitted over great distances to fend off viral infection.

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image: Inactive Actin

Inactive Actin

By | May 1, 2014

Clathrin-mediated endocytosis shuts down during mitosis in eukaryotic cells because all of the required actin is hoarded by the cytoskeleton.

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