The Literature

» developmental biology, cancer and physiology

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image: Tumor Traps

Tumor Traps

By | April 1, 2016

After surgery to remove a tumor, neutrophils recruited to the site spit out sticky webs of DNA that aid cancer recurrence.

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image: Fungal Security Force

Fungal Security Force

By | February 1, 2016

In yew trees, Taxol-producing fungi function as an immune system to ward off pathogens.

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image: Managing Methylation

Managing Methylation

By | January 1, 2016

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

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image: Telomerase Overdrive

Telomerase Overdrive

By | January 1, 2016

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

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image: Adding Padding

Adding Padding

By | November 1, 2015

Adipogenesis in mice has alternating genetic requirements throughout the animals’ lives.

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image: Fat Saps Muscle

Fat Saps Muscle

By | November 1, 2015

The accumulation of fat within skeletal muscle, as happens with obesity, diminishes muscle performance.

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image: Rethinking Lymphatic Development

Rethinking Lymphatic Development

By | August 1, 2015

Four studies identify alternative origins for cells of the developing lymphatic system, challenging the long-standing view that they all come from veins.

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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