The Literature

» disease/medicine, structural biology and cancer

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Cadherin Connection

Cadherin Connection

By | December 1, 2014

A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells.

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image: Going Long

Going Long

By | April 1, 2014

Researchers discover a tool to trigger an uncommon strategy cancer cells can use to lengthen their telomeres.

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image: Stem Cell Alter Egos

Stem Cell Alter Egos

By | April 1, 2014

Researchers show that cancer stem cells can exist in two distinct and interconvertible states.

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image: Exosome Tentacles

Exosome Tentacles

By | March 1, 2014

Unlike the usual smooth, spherical shape of exosomes, glioblastoma-derived exosomes appear to have long nanofilaments protruding from their surfaces.

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image: Intracellular Spirals

Intracellular Spirals

By | December 1, 2013

Membrane twists connect stacked endoplasmic reticulum sheets.

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image: Waking Cancer Cells

Waking Cancer Cells

By | December 1, 2012

A protein called Coco rouses dormant breast cancer cells in the lung.

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image: Viral Skeleton

Viral Skeleton

By | November 1, 2012

A newly discovered family of tubulins—members of the cytoskeleton—encoded by bacteriophages plays a role in arranging the location of DNA within virus’s bacterial host.

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image: DNA, Contortionist

DNA, Contortionist

By | August 1, 2012

The DNA forms known as G-quadruplexes are finally discovered in human cells.

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image: Lymphatic Lines

Lymphatic Lines

By | August 1, 2012

Lymphatic vessels grow towards two chemokines, revealing signals that could be important in cancer metastasis.

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