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image: Managing Methylation

Managing Methylation

By | January 1, 2016

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

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image: Telomerase Overdrive

Telomerase Overdrive

By | January 1, 2016

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

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image: Carry-On Luggage

Carry-On Luggage

By | December 1, 2015

Without a vacuole, cell-cycle progression stalls out in yeast cells.

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image: The Regenerators

The Regenerators

By | September 1, 2015

A molecular signature makes it possible to trace the details of hair cell replacement in the mammalian inner ear.

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Cadherin Connection

Cadherin Connection

By | December 1, 2014

A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells.

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image: Nuclear Pore QA

Nuclear Pore QA

By | December 1, 2014

A known membrane-remodeling complex earns a newly identified role as a quality-assurance director during the assembly of nuclear pores.

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image: Going Long

Going Long

By | April 1, 2014

Researchers discover a tool to trigger an uncommon strategy cancer cells can use to lengthen their telomeres.

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