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image: Inner Ear Undertakers

Inner Ear Undertakers

By | September 1, 2015

Support cells in the inner ear respond differently to two drugs that kill hair cells.

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The Regenerators

By | September 1, 2015

A molecular signature makes it possible to trace the details of hair cell replacement in the mammalian inner ear.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.

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Long Live Collagen

By | March 1, 2015

Increased collagen expression is a common feature of many different pathways to extended longevity in worms.

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Nuclear Pore QA

By | December 1, 2014

A known membrane-remodeling complex earns a newly identified role as a quality-assurance director during the assembly of nuclear pores.

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Mitochondria Munchers

By | November 1, 2014

Glial cells consume mitochondria released by neurons in the optic nerve.

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Cone Cell Correctors

By | October 1, 2014

In mice, adult cone cell outer segments and their visual functions deteriorate if two microRNAs are not present.

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Beneficial Brew

By | June 1, 2014

Drinking green tea appears to boost the activity of DNA repair enzymes.

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