The Literature

» genetics & genomics and physiology

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image: Aneuploid Responses

Aneuploid Responses

By | May 1, 2016

A recent exchange of papers is divided over the evidence for compensatory gene expression among wild strains of aneuploid yeast.

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image: Managing Methylation

Managing Methylation

By | January 1, 2016

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

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image: Telomerase Overdrive

Telomerase Overdrive

By | January 1, 2016

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

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image: Fat Saps Muscle

Fat Saps Muscle

By | November 1, 2015

The accumulation of fat within skeletal muscle, as happens with obesity, diminishes muscle performance.

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image: Rethinking Lymphatic Development

Rethinking Lymphatic Development

By | August 1, 2015

Four studies identify alternative origins for cells of the developing lymphatic system, challenging the long-standing view that they all come from veins.

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image: Metazoans in the DNAi Club

Metazoans in the DNAi Club

By | July 1, 2015

A chance discovery results in the first report of DNA-based gene silencing in an animal.

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image: Not So Noncoding

Not So Noncoding

By | June 1, 2015

An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.

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image: Silencing Surprise

Silencing Surprise

By | June 1, 2015

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.

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image: Looking for Latent HIV

Looking for Latent HIV

By | May 1, 2015

Sequencing HIV integration sites suggests that clonally expanded T-cell populations may not be the main source of latent virus.

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image: Rethinking Telomeres

Rethinking Telomeres

By | March 1, 2015

Not only do telomeres protect the ends of chromosomes, they also modulate gene expression over cells’ lifetimes.

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