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genetics & genomics, cell & molecular biology

AAAAA Is for Arrested Translation
Ruth Williams | Jul 24, 2015 | 3 min read
Multiple consecutive adenosine nucleotides can cause protein translation machinery to stall on messenger RNAs.
Extra DNA Base Discovered
Jef Akst | Jun 23, 2015 | 1 min read
An epigenetic variant of cytosine is stable in the genomes of living mice, suggesting a possible expansion of the DNA alphabet.
A Benefit of Failed Pregnancy?
Ruth Williams | Apr 9, 2015 | 3 min read
Scientists find a common genetic variant in mothers that decreases the chance of successful pregnancy.
Setbacks and Great Leaps
Sue Armstrong | Apr 1, 2015 | 3 min read
The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.
Cancer Kismet
Jenny Rood | Apr 1, 2015 | 4 min read
Fate mapping allows researchers to follow cancer progression from its cell type of origin.
Resisting Cancer
George Klein | Apr 1, 2015 | 9 min read
If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.
From Many, One
Elena E. Giorgi | Apr 1, 2015 | 10+ min read
Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?
Book Excerpt from p53
Sue Armstrong | Mar 31, 2015 | 4 min read
In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.
Weiwei Dang: Epigenetics in Aging
Jef Akst | Mar 1, 2015 | 3 min read
Assistant Professor, Huffington Center On Aging, Baylor College of Medicine. Age: 38
Evolutionary Rewiring
Ruth Williams | Feb 26, 2015 | 3 min read
Strong selective pressure can lead to rapid and reproducible evolution in bacteria.
Enzyme Design
Jef Akst | Dec 3, 2014 | 2 min read
Researchers create synthetic enzymes in the lab, encoded by artificial genetic material.
Mom’s Mitochondria Affect Pup Longevity
Ruth Williams | Oct 9, 2014 | 3 min read
Mitochondrial mutations inherited from the mother can shorten a mouse’s lifespan.
Heritable Histones
Ruth Williams | Sep 18, 2014 | 3 min read
Scientists show how roundworm daughter cells remember the histone modification patterns of their parents.
How Hummingbirds Taste Nectar
Ruth Williams | Aug 21, 2014 | 3 min read
Hummingbirds perceive sweetness through a receptor with which other vertebrates taste savory foods. 
Week in Review: July 21–25
Tracy Vence | Jul 25, 2014 | 3 min read
Blood-based Alzheimer’s diagnostics; CRISPR cuts out HIV; Leishmania and the sand fly microbiome; deconstructing the lionfish science fair debacle
Week in Review: July 14–18
Tracy Vence | Jul 18, 2014 | 3 min read
Converting heart muscle to pacemaker cells in pigs; alternative splicing and the human proteome; questioning a reported yogurt mold-illness link; H. pylori swiftly find mouse stomach injuries
Interactome Analysis
Jyoti Madhusoodanan | Jun 17, 2014 | 2 min read
Study examines tissue-specific protein interactions linked to hereditary diseases.
Week in Review: May 26–30
Tracy Vence | May 30, 2014 | 4 min read
Human proteome cataloged; island-separated crickets evolved silence; molecule shows promise for combatting coronaviruses; study replication etiquette; another call for STAP retraction
Week in Review: April 28–May 2
Tracy Vence | May 2, 2014 | 3 min read
Male scientists stress mice out; using SCNT to reprogram adult cells; acetate can reach mouse brain, reduce appetite; WHO sounds “post-antibiotic era” alarm
Week in Review: April 21–25
Tracy Vence | Apr 25, 2014 | 3 min read
Evolution of Y chromosome; delivering gene with “bionic ears”; diversity of an important cyanobacterium; charting genome-sequencing progress; blockbuster pharma deals
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