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The Literature

» genetics & genomics and disease/medicine

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image: Metazoans in the DNAi Club

Metazoans in the DNAi Club

By | July 1, 2015

A chance discovery results in the first report of DNA-based gene silencing in an animal.

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image: Not So Noncoding

Not So Noncoding

By | June 1, 2015

An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.

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image: Silencing Surprise

Silencing Surprise

By | June 1, 2015

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.

3 Comments

image: Looking for Latent HIV

Looking for Latent HIV

By | May 1, 2015

Sequencing HIV integration sites suggests that clonally expanded T-cell populations may not be the main source of latent virus.

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image: Rethinking Telomeres

Rethinking Telomeres

By | March 1, 2015

Not only do telomeres protect the ends of chromosomes, they also modulate gene expression over cells’ lifetimes.

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image: Nibbled? No Problem

Nibbled? No Problem

By | February 1, 2015

Making extra copies of their genomes allows some plants to better withstand damage.

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image: A Long Line of LINEs

A Long Line of LINEs

By | September 1, 2014

Different mechanisms repress mobile DNA elements in human embryonic stem cells depending on the elements’ evolutionary ages.

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image: Sexless Hook-Up

Sexless Hook-Up

By | September 1, 2014

Genome fusion at stem graft junctions can generate new plant species.

1 Comment

image: Loss of Potential

Loss of Potential

By | June 1, 2013

In the fruit fly, the ability of neural stem cells to make the full repertoire of neurons is regulated by the movement of key genes to the nuclear periphery.

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image: Fast Worms

Fast Worms

By | January 1, 2013

A microfluidic device scans individual C. elegans for abnormal traits and sorts wild-type animals from mutants.

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