Critic at Large

» cell & molecular biology and cancer

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image: Pet Scans

Pet Scans

By , , and | April 1, 2016

Studying tumor development and treatment in dogs and cats, in parallel with research on rodents and humans, could improve the successful translation of new cancer drugs.

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

1 Comment

image: The Challenges of Precision

The Challenges of Precision

By | April 1, 2015

Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.

1 Comment

image: Enhanced Enhancers

Enhanced Enhancers

By | November 1, 2014

The recent discovery of super-enhancers may offer new drug targets for a range of diseases.

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image: Fighting Cancer with Nanomedicine

Fighting Cancer with Nanomedicine

By | April 1, 2014

Nanotechnology-based therapeutics will revolutionize cancer treatment.

2 Comments

image: Remaking Nature

Remaking Nature

By | August 1, 2013

Synthetic biologists need to work together with conservationists to understand the environmental consequences of this new technology.

6 Comments

image: Cancer Clinical Trials of Tomorrow

Cancer Clinical Trials of Tomorrow

By | April 1, 2013

Advances in genomics and cancer biology will alter the design of human cancer studies.

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image: Avoiding Animal Testing

Avoiding Animal Testing

By | December 1, 2011

Advances in cell-culture technologies are paving the way to the complete elimination of animals from the laboratory.

82 Comments

image: Vive la Différence

Vive la Différence

By | September 1, 2011

Measuring how individual cells differ from each other will enhance the predictive power of biology.

6 Comments

image: Imagining a Cure

Imagining a Cure

By | April 11, 2011

For cancer patients, close is not good enough.

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    The European Patent Office will grant patent rights over the use of CRISPR in all cell types to a University of California team, contrasting with a recent decision in the U.S.

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    With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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    Daily News Rethinking a Cancer Drug Target

    The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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