Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

Fluorescence indicates chlorotoxin binding to medulloblastoma cells in a mouse (right). Credit: Image by Mandana Veiseh, courtesy of AACR" />Fluorescence indicates chlorotoxin binding to medulloblastoma cells in a mouse (right). Credit: Image by Mandana Veiseh, courtesy of AACR Within minutes after being stung by the scorpion known as the deathstalker (Leiurus quinquestriatus), weakness starts to kick in. The feeling quickly spreads, paralyzing its prey (typically insects) for hours -

As the importance of genomic copy number variations for health and disease becomes clearer, researchers are creating new ways to detect these changes in the genome.

Tagged for Cleansing Not just the cell's trash and recycling center, the ubiquitin system controls complex cellular pathways with elegant simplicity and precision. By Michele Pagano have always gravitated toward order. I may even take it a bit too far according to friends who liken my office to a museum. However, I like to think it not a compulsion, but a Feng Shui approach to life. With this need for order, I may have been better suited to

This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

A lack of methodological detail in the published literature threatens the foundation of scientific discourse.

The U.S. government's environmental regulatory apparatus is about to be challenged in a fundamental way by a novel technology that can--for the first time--measure whether there is cancer risk from minute quantities of chemicals and nuclear radiation. A newly developed supersensitive method--up to 100,000 times more sensitive than any now available--can establish whether genetic material in human cells has been damaged, an initial step that can lead to cancer. Scientific advances inevitably ca

An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.