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DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Digital illustration of AI concept
How should we proceed with image-analyzing AI?
Ida Emilie Steinmark, PhD | Aug 1, 2023 | 2 min read
Algorithms can now glean ever more molecular and genetic information from images of stained tissue, but some researchers worry that we can’t follow their logic.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Lasker Award winner Piet Borst sits at his desk.
A Journey With Metabolism, Parasites, and Cancer
Laura Tran, PhD | Sep 21, 2023 | 7 min read
Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.
Zebrafish with fluorescent nervous system in green.
Oust the Mouse: A Plan to Reduce Mammal Use in Drug Development
Natalia Mesa, PhD | Mar 15, 2022 | 7 min read
The Scientist spoke to Mount Desert Island Biological Laboratory’s Jim Strickland about the institute’s new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models.
Biology’s New Supermodel
Megan Scudellari | Jul 20, 2011 | 5 min read
Induced pluripotent stem cells are biology’s hottest new tool for understanding human disease.
Molecular Approaches Breathe New Life Into Sports Medicine
Sara Latta | Jul 20, 1997 | 7 min read
Now that summer is in full swing, all but the most dedicated couch potatoes are playing on departmental softball teams, hitting the tennis courts, or laboring in the garden. For a growing number of scientists, however, exercise is more than a seasonal diversion-it's the focus of a thriving discipline that integrates molecular and cellular biology, physiology, nutrition, and behavioral sciences. One important trend, not only in exercise science but also in physiology, is the integration of mole
A nude (hairless) mouse, typically used in biomedical and drug discovery research methods that rely on immunodeficient mouse strains.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD | Aug 31, 2022 | 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Image of pancreatic organoids under a microscope with immunofluorescent staining
Pancreatic Organoids Take the Stage
Laura Tran, PhD | Dec 1, 2023 | 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.

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