Critic at Large

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy

Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy

By | February 1, 2017

What can be done to lower development costs and drug prices?

4 Comments

image: Opinion: Ethical Considerations of “Three-Parent” Babies

Opinion: Ethical Considerations of “Three-Parent” Babies

By | December 22, 2016

Mitochondrial replacement therapy raises important societal and ethical concerns, but should be embraced for its utility in preventing disease.

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image: Opinion: An Ethical Code for Conferences

Opinion: An Ethical Code for Conferences

By | December 2, 2016

This fundamental form of scientific communication is threatened by modern recording technology and researchers who refuse to adhere to an age-old ethical code. 

4 Comments

image: Opinion: Not All Genetic Databases Are Equal

Opinion: Not All Genetic Databases Are Equal

By | December 1, 2016

Sorting out which data sets are clinical-grade is key to helping patients.

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image: Opinion: Aging, Just Another Disease

Opinion: Aging, Just Another Disease

By | November 1, 2016

No longer considered an inevitability, growing older should be and is being treated like a chronic condition. 

26 Comments

image: Opinion: Fixing Science’s Human Bias

Opinion: Fixing Science’s Human Bias

By and | September 1, 2016

It’s time to accelerate the conversation about why the research community is still not diverse.

3 Comments

image: Opinion: Our Inner Caveman

Opinion: Our Inner Caveman

By | August 1, 2016

The modern human brain evolved in social and environmental settings very unlike today’s. Despite our cultural and technological progress, tribal instincts remain.

2 Comments

image: The Global Science Era

The Global Science Era

By | May 1, 2016

As international collaboration becomes increasingly common, researchers must work to limit their own biases and let cultural diversity enhance their work.

2 Comments

image: Pet Scans

Pet Scans

By , , and | April 1, 2016

Studying tumor development and treatment in dogs and cats, in parallel with research on rodents and humans, could improve the successful translation of new cancer drugs.

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  1. Opinion: Why I Published in a Predatory Journal
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    My “colleagues” and I at the fictitious Arthur Vandelay Urological Research Institute were surprised to find our bogus “uromycitisis” case report swiftly accepted, with only minor revisions requested.

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