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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Screening  with CRISPR

Screening with CRISPR

By | June 1, 2016

Ever-improving CRISPR-based tools are already ripe for large-scale genetic screens.

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image: Pulling It All Together

Pulling It All Together

By | April 1, 2016

Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.

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image: Messages in the Noise

Messages in the Noise

By | August 1, 2015

After spending more than a decade developing tools to study patterns in gene sequences, bioinformaticians are now working on programs to analyze epigenomics data.

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image: Getting Your Sugar Fix

Getting Your Sugar Fix

By | April 1, 2015

A guide to glycan microarrays

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image: In Custody

In Custody

By | April 1, 2015

Expert tips for isolating and culturing cancer stem cells

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image: Nuclear Cartography

Nuclear Cartography

By | October 1, 2014

Techniques for mapping chromosome conformation

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image: Entry Requirements

Entry Requirements

By | September 1, 2014

Recent developments in cell transfection and molecular delivery technologies

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image: Surviving the Ice Age

Surviving the Ice Age

By | September 1, 2014

A beginner’s guide to freezing and thawing pluripotent stem cells

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image: Hear Ye, Hear Ye

Hear Ye, Hear Ye

By | May 1, 2014

Tools for tracking quorum-sensing signals in bacterial colonies

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