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tag biomarkers microscopy mass spectrometry disease medicine

An Introduction to Metabolomics
An Introduction to Metabolomics
Rebecca Roberts, PhD | Oct 17, 2023 | 5 min read
As the closest reflection of biological phenotype, metabolomics provides critical information about human health and disease.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
A Revolutionary Approach to Biomarker Discovery
Emanuel F. Petricoin and Lance A. Liotta | Nov 1, 2006 | 10+ min read
A Revolutionary Approach to Biomarker Discovery Immunoassays coupled with mass spectrometrycould reveal new dimensions in the blood  By Emanuel F. Petricoin and Lance A. Liotta ARTICLE EXTRAS Proteomics: Promise and ProblemsSuch early disease detection doesn't always mean longer life, write JENNIFER MILLER and BARNETT KRAMER. INFOGRAPHIC: The Peptidome Hypothesis:What does a disease signature look like in the blood? Serum Proteomics ScrutinizedSELDI-TOF st
Mapping Brain Proteins
Devika G. Bansal | Feb 1, 2018 | 7 min read
Researchers are using souped-up mass spectrometry to localize proteins within brain cells.
Quantitating Glycans for Biomarker Discovery
Amanda Keener | Aug 27, 2017 | 8 min read
Techniques for comparing the relative abundances of glycans and glycoproteins in clinical samples
My Mighty Mouse
Megan Scudellari | Apr 1, 2015 | 10+ min read
Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Reducing Risks, Maximizing Impact with Cancer Biomarkers
Athos Gianella-Borradori | Mar 14, 2004 | 3 min read
Brad FitzpatrickBiomarkers measure drug-induced changes in a patient's blood or tissue. Such changes can confirm drug activity and thereby help select patients more likely to respond to treatment. These biochemicals are revolutionizing cancer drug development.It's a revolution sorely needed. A recent Nature Medicine story described 2003 as filled "with hype and hope for cancer drugs ... [The year] saw no shortage of cancer headlines ... But recent successes have not been unequivocal, and emphasi
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
2017 Top 10 Innovations
The Scientist | Dec 1, 2017 | 10+ min read
From single-cell analysis to whole-genome sequencing, this year's best new products shine on many levels.

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