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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: How to Build Bioinformatic Pipelines Using Galaxy

How to Build Bioinformatic Pipelines Using Galaxy

By | August 1, 2016

A point-and-click interface alternative to command-line tools that allows researchers to easily create, run, and troubleshoot serial sequence analyses

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image: The Genetic Components of Rare Diseases

The Genetic Components of Rare Diseases

By | July 1, 2016

Techniques for determining which genes or genetic variants are truly detrimental

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image: Screening  with CRISPR

Screening with CRISPR

By | June 1, 2016

Ever-improving CRISPR-based tools are already ripe for large-scale genetic screens.

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image: Scaling to Singles

Scaling to Singles

By | May 1, 2016

Tips for tracing transcription in individual cells

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image: Pulling It All Together

Pulling It All Together

By | April 1, 2016

Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.

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image: Dial It Up, Dial It Down

Dial It Up, Dial It Down

By | March 1, 2016

Newer CRISPR tools for manipulating transcription will help unlock noncoding RNA’s many roles.

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image: Spoiler Alert

Spoiler Alert

By | March 1, 2016

How to store microbiome samples without losing or altering diversity

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image: Reveling in the Revealed

Reveling in the Revealed

By | January 1, 2016

A growing toolbox for surveying the activity of entire genomes

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image: Cracking the Complex

Cracking the Complex

By | November 1, 2015

Using mass spec to study protein-protein interactions

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