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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Remote Mind Control

Remote Mind Control

By | November 1, 2015

Using chemogenetic tools to spur the brain into action

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image: Into the Limelight

Into the Limelight

By | October 1, 2015

Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.

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image: In Custody

In Custody

By | April 1, 2015

Expert tips for isolating and culturing cancer stem cells

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image: Eye on the Fly

Eye on the Fly

By | January 1, 2015

Automating Drosophila behavior screens gives researchers a break from tedious observation, and enables higher-throughput, more-quantitative experiments than ever before.

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image: Mouse Traps

Mouse Traps

By | November 1, 2014

How to avoid pitfalls in assays of mouse behavior

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image: Surviving the Ice Age

Surviving the Ice Age

By | September 1, 2014

A beginner’s guide to freezing and thawing pluripotent stem cells

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image: Lights, Camera, Action

Lights, Camera, Action

By | January 1, 2014

A guide for doing in vivo microscopy on neurons in the mammalian brain

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image: Synapses on Stage

Synapses on Stage

By | November 1, 2013

Light microscopy techniques that spotlight neural connections in the brain

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image: Scents in a Flash

Scents in a Flash

By | October 1, 2013

The modern technique of optogenetics stimulates the complex act of smelling with a simple flash of light.

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