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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Messages in the Noise

Messages in the Noise

By | August 1, 2015

After spending more than a decade developing tools to study patterns in gene sequences, bioinformaticians are now working on programs to analyze epigenomics data.


image: Getting Your Sugar Fix

Getting Your Sugar Fix

By | April 1, 2015

A guide to glycan microarrays

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image: In Custody

In Custody

By | April 1, 2015

Expert tips for isolating and culturing cancer stem cells

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image: Nuclear Cartography

Nuclear Cartography

By | October 1, 2014

Techniques for mapping chromosome conformation


image: Entry Requirements

Entry Requirements

By | September 1, 2014

Recent developments in cell transfection and molecular delivery technologies


image: Surviving the Ice Age

Surviving the Ice Age

By | September 1, 2014

A beginner’s guide to freezing and thawing pluripotent stem cells


image: Hear Ye, Hear Ye

Hear Ye, Hear Ye

By | May 1, 2014

Tools for tracking quorum-sensing signals in bacterial colonies


image: Gene Silencing Is Golden

Gene Silencing Is Golden

By | August 1, 2013

A beginner’s how-to on RNAi screening in mammalian cells


image: Buying Cell-Culture Products

Buying Cell-Culture Products

By | March 1, 2013

A survey of The Scientist readers reveals who buys cell-growth products from whom, and why.


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