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Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Fluorescence microscopy image of cells expressing fluorescent biosensors. Green and magenta fluorescence is observed outside of the cell nuclei.
Choosing Fluorescent Reagents for Every Live Cell Application
The Scientist and MilliporeSigma | Nov 30, 2022 | 4 min read
Scientists gain unique insights into active biological processes with specific fluorescent probes, dyes, and biosensors.
Top 10 Innovations 2014
The Scientist | Dec 1, 2014 | 10+ min read
The list of the year’s best new products contains both perennial winners and innovative newcomers.
Creative Emulsification
Sabrina Richards | Nov 1, 2012 | 8 min read
Enhancing data collection from emulsion PCR reactions: three case studies
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Fluorescence Spectroscopy Shedding Light On Complex Biosystems
Holly Ahern | Jun 9, 1996 | 9 min read
Complex Biosystems Spectroscopic detection of fluorescent molecules, either those found naturally or those colored with fluorescent dyes, has created new research possibilities for scientists who study proteins and DNA. With photonic instruments like spectrophotometers and spectrofluorimeters, life scientists can measure the low-intensity light emitted from fluorescent molecules. "Because the character of the light emitted from a molecule changes in respect to the environment the molecule is i
A Sharper Image
Bob Sinclair | Apr 29, 2001 | 10+ min read
Medical miracles abound, yet cancer continues to be a complex and challenging problem. "Cancer" is actually a generic, catchall term for the malignant tumors that are found in well over a hundred different diseases, but the basic concept is simple enough--a gene goes wrong and a tumor grows. Unfortunately, the reality is more complicated, involving an intricate sequence of phenomena and interactions in just a handful of the body's tens-of-trillions of cells. And therein lies the problem for rese
Top Ten Innovations 2010
Megan Scudellari | Dec 1, 2010 | 10+ min read
By The Scientist Staff Top Ten Innovations 2010 Innovative products that have the life science community buzzing. As the global economy continues to pull out of its recent precipitous nosedive, one mantra rings true from Beijing to Boston—innovation can save us. If developing interesting new technologies and products really is the lifeblood of economic health, then the life sciences industry is innovation’s beating heart. The Scientist rec
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Dead Again: Adventures in Apoptosis
Laura Defrancesco | Mar 1, 1999 | 9 min read
Date: March 1, 1999Caspase Substrates and Inhibitors, Apoptosis ProductsCast of Characters Apoptosis is no less a hot topic than it was a year ago when LabConsumer first looked at the available tools for studying this complex phenomenon.1 In that intervening time, roughly 20 papers per day have been published on apoptosis, an issue of Science devoted to apoptosis has been published,2 and countless new pieces have been added to the puzzle. To get an idea of the complexity of apoptosis in higher

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