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Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
a close up photo of a black dog nose with blond and white whiskers
Dogs: The New COVID-19 Rapid Test
Kerry Grens | May 24, 2021 | 2 min read
Two studies this month point to pooches’ quick detection of SARS-CoV-2 on material that touched the skin of infected participants, although the pups’ accuracy does not match that of RT-PCR.
TAg
Jeffrey Perkel | Apr 29, 2001 | 2 min read
Antigen-specific T lymphocytes must be quantified in order to gauge the quality of an immune response. Typically this is accomplished using cytotoxicity assays or limiting dilution analysis (LDA), but these techniques are lengthy and provide indirect quantitation. Also, LDA cannot count nonproliferative cells. In 1996, Stanford University's Mark Davis developed an alternative strategy that overcomes these problems.1 Davis generated phycoerythrin-conjugated tetramers of human lymphocyte antigen (
Microbiology Goes High-Tech
Jeffrey M. Perkel | Jun 1, 2012 | 8 min read
Out with toothpicks and pipettors; in with automation.
Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
Tumor microbiome composite
Could Cancer’s Microbiome Help Diagnose and Treat the Disease?
Jef Akst | Mar 14, 2022 | 10+ min read
A growing appreciation of the bacterial assemblages that live within tumors has researchers striving to understand and capitalize on their role.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
hannah burrack entomology tobacco budworm caterpillar spotted wing Drosophila coronavirus pandemic covid-19
Amid the COVID-19 Pandemic, Some Scientists Bring the Bench Home
Emma Yasinski | May 13, 2020 | 5 min read
PCR moves into the laundry room, while insect colonies take up residence in the shower.
Innovations Expand Lab Power, Uses Of PCR Technique
Ricki Lewis | Jul 25, 1993 | 8 min read
The gene amplification technique invented by genetics researcher Kary Mullis on a moonlit drive through the northern California hills a decade ago--the polymerase chain reaction (PCR)-- continues to revolutionize the life sciences. Uses in molecular biology research and in diagnostic tests are proliferating, and PCR is even bringing a new molecular approach to such fields as paleontology and epidemiology. The following companies are among those supplying PCR-related products for the resear
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.

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