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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Cracking the Complex

Cracking the Complex

By | November 1, 2015

Using mass spec to study protein-protein interactions

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image: In Custody

In Custody

By | April 1, 2015

Expert tips for isolating and culturing cancer stem cells

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image: Surviving the Ice Age

Surviving the Ice Age

By | September 1, 2014

A beginner’s guide to freezing and thawing pluripotent stem cells

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image: Tailoring Your Proteome View

Tailoring Your Proteome View

By | August 1, 2014

Computational tools can streamline the development of targeted proteomics experiments.  

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image: Bird’s-Eye Proteomics

Bird’s-Eye Proteomics

By | July 1, 2014

A guide to mass spectrometers that can handle the top-down-proteomics challenge

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image: The Sooner, The Better

The Sooner, The Better

By | July 1, 2014

New approaches to diagnosing bacterial infections may one day allow the identification of pathogens and their antibiotic susceptibility in a matter of hours or minutes.

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image: Moving Target

Moving Target

By | June 1, 2014

New mass spectrometry–based techniques are blurring the lines between discovery and targeted proteomics.

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image: Name That Metabolite!

Name That Metabolite!

By | July 1, 2013

A guided tour through the metabolome

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image: Suited to a T

Suited to a T

By | May 1, 2013

Sorting out T-cell functional and phenotypic heterogeneity depends on studying single cells.

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