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Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Infographic: A Yeast Model for Studying Histone Modifications
Infographic: A Yeast Model for Studying Histone Modifications

The methodology involves modifying histones and displaying them on the cell surface for analysis.

The methodology involves modifying histones and displaying them on the cell surface for analysis.

genetics & genomics, cell & molecular biology

Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021 | 3 min read
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
a person in a white lab coat with a blue glove inserting a clear pcr tube into a which thermocycler while holding an orange box
Coronavirus Mutations Could Muddle COVID-19 PCR Tests
Jack J. Lee | May 17, 2021 | 4 min read
Researchers find that SARS-CoV-2 variants can evade primer-probe sets and recommend that diagnostic assays include multiple targets for reliability.
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Present Your Paper in The Scientist’s Journal Club
The Scientist Staff | 1 min read
Apply today to share your cutting-edge research in The Scientist’s Journal Club.
Aphid Salivary Gene May Regulate Gall Color
Asher Jones | May 1, 2021 | 2 min read
Whether the galls that aphids make on witch hazel leaves are red or green is associated with a gene expressed in the insects’ salivary glands.
obituary, obituaries, microbiology, molecular genetics, biochemistry, bioinformatics, Stanford University, University of Southern California, cell & molecular biology
Laurence “Larry” Kedes, Molecular Geneticist, Dies at 83
Amanda Heidt | Apr 26, 2021 | 4 min read
In addition to isolating the first protein-coding gene from a eukaryote, Kedes furthered scientists’ understanding of actin genes and also laid the foundations for modern DNA databases such as GenBank.
Modern Approaches to qPCR
The Scientist | 1 min read
Download this ebook to learn how updated qPCR instruments provide optimal thermal performance and data connectivity!
Cancer May Be Driven by DNA Outside of Chromosomes
Paul Mischel | Apr 1, 2021 | 10+ min read
In the last decade, researchers have come to realize that tumors harbor bits of extrachromosomal DNA that can drive malignancy.
Contributors
Asher Jones and Kerry Grens | Apr 1, 2021 | 3 min read
Meet some of the people featured in the April 2021 issue of The Scientist.
Advances in Nucleic Acid Sequencing
The Scientist | 1 min read
Download this eBook to learn how new sequencing methods revolutionize genetics research!
“Rogue” Protein Could Contribute to Humans’ High Cancer Rates
Asher Jones | Apr 1, 2021 | 2 min read
A mutant protein called Siglec-XII may promote carcinoma progression in humans, but inactivation of its gene seems to avoid the problem, according to a study.
Infographic: The Role of Extrachromosomal DNA in Cancer
Paul Mischel | Apr 1, 2021 | 2 min read
Researchers are uncovering how circular bits of DNA found in some cancer cells can help tumors evolve and kill.
Mary Jeanne Kreek, heroin, addiction, methadone, drug addiction, The Rockefeller University,
Mary Jeanne Kreek, Methadone Developer, Dies at 84
Asher Jones | Mar 31, 2021 | 2 min read
A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.
Lab-Grown Mouse Embryos Form Limbs and Organs
Lisa Winter | Mar 19, 2021 | 3 min read
The embryos completed one-third of their total gestation outside of a uterus.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
UPDATED
Ebola, virus, Guinea, West Africa, outbreak
Ebola Outbreak in Guinea Originated from Past Epidemic
Asher Jones | Mar 15, 2021 | 2 min read
Genetic analyses suggest that the virus came from a patient who survived the 2013–2016 West African outbreak.
Derek Applewhite’s Actin Research Inspires the Next Generation
Lisa Winter | Mar 1, 2021 | 4 min read
The biologist’s undergraduate-centered lab allows students to play a meaningful role in research.
Gene-Edited Organoids Explore Neanderthal Brain Function
Jef Akst | Feb 12, 2021 | 3 min read
Using CRISPR to swap an archaic variant of the NOVA1 gene into human stem cells, researchers create organoids with neurodevelopmental differences from those carrying modern DNA.
retina atrophic age-related macular degeneration amd alu line-1 l1 retrotransposon cytoplasm cdna reverse transcription replication genome dna
Human Cells Can Synthesize DNA in Their Cytoplasm
Alejandra Manjarrez, PhD | Feb 8, 2021 | 4 min read
While studying a degenerative eye disease, researchers find the first evidence that cells produce endogenous DNA in the cytoplasm. Drugs that block this activity are linked with reduced risk of atrophic age-related macular degeneration.
2021 life science predictions innovations biotech mrna single-cell sequencing diagnostics
Experts Predict the Hottest Life Science Tech in 2021 and Beyond
Bob Grant | Feb 1, 2021 | 7 min read
Last year’s Top 10 Innovations judges look into their crystal balls.
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