Genomic analysis of an oak tree that lived during Napoleon’s time supports the idea that plants somehow avoid the accumulation of mutations in their stem cells.
Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.
A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.
Elaine Fuchs has worked on adult stem cells since before they were so named, figuring out how multipotent epidermal cells renew or turn into skin or hair follicles.
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.