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Chemogenetics Method Uses Anti-Smoking Drug to Control Cells
Chemogenetics Method Uses Anti-Smoking Drug to Control Cells
A new set of engineered receptors responds to an FDA-approved drug to provide the most potent chemogenetic toolkit to date.
A new set of engineered receptors responds to an FDA-approved drug to provide the most potent chemogenetic toolkit to date.
techniques, cell & molecular biology
Revealed: New Cortical Neuron Types
Ashley P. Taylor | Oct 31, 2018 | 2 min read
A pair of mouse studies describes neuronal subpopulations not identified before and some of their functions.
Image of the Day: Shrink Ray
Jef Akst | Oct 30, 2018 | 1 min read
A near-infrared laser warps a tissue culture surface to mimic natural cellular environments.
Image of the Day: Transgenic Axolotl
Kerry Grens | Oct 3, 2018 | 1 min read
Lineage tracing reveals how cells help the salamanders regrow chopped-off limbs.
RNA Detection Tool Debate Flares Up at ACS Meeting
Katarina Zimmer | Sep 5, 2018 | 5 min read
Researchers have flagged several issues with so-called SmartFlares over the years, and it’s still unclear why they don’t appear to work under certain circumstances.
The Cell’s Integrated Circuit: A Profile of Lucy Shapiro
Anna Azvolinsky | Aug 1, 2018 | 9 min read
Shapiro helped to found the field of systems biology.
How to Track Metabolites in Tissues Using NMR
Katherine Bourzac | Aug 1, 2018 | 7 min read
Whether it’s aligning software or prepping samples, researchers share their tips for studying the metabolome with this underused approach.
Roland Nardone, Advocate for Cell-Line Authentication, Dies
Kerry Grens | Jul 11, 2018 | 2 min read
The Catholic University of America professor was also known for his summer workshops on the latest techniques.
Image of the Day: Beating Heart
Sukanya Charuchandra | Jul 2, 2018 | 1 min read
Scientists at the Allen Institute for Cell Science have developed an open-source stem cell line with fluorescent tags for cardiac cells.
Image of the Day: X-Ray Vision
Sukanya Charuchandra | Jun 28, 2018 | 1 min read
Using a unique microscope, researchers looked inside a yet-to-be identified pseudoscorpion from Peru.
Magnetic Microrobots Deliver Cells Into Living Animals
Sukanya Charuchandra | Jun 27, 2018 | 1 min read
The miniscule carriers successfully transported and released live cells at a particular location within living mice.
Image of the Day: Throw the Switch
Sukanya Charuchandra | Jun 27, 2018 | 1 min read
A computer model of the eye can predict the consequences of altering the neural pathways of vision.
Image of the Day: Remodeled
Sukanya Charuchandra | Jun 25, 2018 | 1 min read
Researchers use CRISPR-Cas9 to create transgenic Hydractinia symbiolongicarpus, a cnidarian, for the first time.
Image of the Day: Lego Microscopy
The Scientist Staff | May 16, 2018 | 1 min read
With open-source software and Lego hardware, researchers have created a low-cost, automated method for cellular fluorescence microscopy.
Infographic: From Sediments to Sequences
Catherine Offord | Feb 28, 2018 | 2 min read
How to analyze ancient proteins
Infographic: Combo Method of Stem Cell Generation
Ruth Williams | Nov 30, 2017 | 1 min read
Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.
Mass Resignation from Scientific Reports’s Editorial Board
Catherine Offord | Nov 6, 2017 | 2 min read
Nineteen researchers have stepped down after the journal decided not to retract a paper that they say plagiarized the work of a Johns Hopkins biomedical scientist.
Technique Rapidly Generates Monoclonal Antibodies In Vitro
Josh P. Roberts | Jul 25, 2017 | 3 min read
A new method stimulates B cells to make human antigen-specific antibodies, obviating the need for vaccinating blood donors or hunting for rare B cells.
Infographic: How to Build a Synthetic Sensor
Ruth Williams | Nov 30, 2016 | 1 min read
Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.
How to Track Translation in Living Cells
Ruth Williams | Oct 1, 2016 | 4 min read
Four independent research groups develop techniques for visualizing peptide production in living cells.