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tag evolution hiv infectious disease cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
Molecular Biology
The Scientist Staff | Jan 6, 1991 | 1 min read
B. Berkhout, R.H. Silverman, K.-T. Jeang, "Tat trans-activates the human immunodeficiency virus through a nascent RNA target," Cell, 59, 273-82, 20 October 1989. Ben Berkhout (National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Md.): "The unique feature of this study was the use of RNA-refolding mutagenesis. Rearrangement of RNA structures was first described by Charles Yanofsky [Stanford University] to explain the process of transcriptional attenuation ["Transcription atten
Artist&rsquo;s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Holly Barker, PhD | Aug 5, 2022 | 4 min read
Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Sino Biological Deposits Recombinant Omicron Proteins and Antibodies to BEI Resources
Sino Biological Deposits Recombinant Omicron Proteins and Antibodies to BEI Resources
Sino Biological | Dec 31, 2021 | 2 min read
Sino Biological, Inc. (SZSE: 301047) has recently deposited reagents for the Omicron variant, including recombinant proteins to Spike and Nucleocapsid, and antibody products to BEI Resources, a central repository for reagents to support infectious disease research.
An Eclectic Look at Infectious Diseases
Ricki Lewis | Aug 20, 2000 | 7 min read
Graphic: Cathleen Heard A week after the controversial XIII International AIDS Conference in Durban, South Africa, a much smaller gathering in Atlanta took a broader view of the current emergence and reemergence of many infectious diseases. The International Conference on Emerging Infectious Diseases 2000, held July 16-19, attracted more than 2,000 attendees representing 35 nations. The Centers for Disease Control and Prevention (CDC), the American Society for Microbiology, the Council of State
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Infectious Curiosity
Jessica Wapner | Dec 1, 2010 | 3 min read
By Jessica Wapner Infectious Curiosity The Hepatitis C virus NS3 serine protease (in gray) James Griffith, Vertex Pharmaceuticals The course of virologist Charlie Rice’s career changed with one phone call in 1989. Then at Washington University in St. Louis, Rice was the country’s leading yellow fever expert. The voice on the other end of the line belonged to Stephen Feinstone, an FDA scientist asking about a vaccine for the disease that had just won agenc
A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.

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