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tag neuroscience nih disease medicine culture

The Breakthrough Prize ?Trophy
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD | Sep 14, 2023 | 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Neurons (green) fire differently depending on whether the astrocytes (red) they are grown with are cultivated from people with or without fragile X.
Astrocytes Fuel Erratic Firing in Fragile X Neurons
Lauren Schenkman, Spectrum | May 30, 2023 | 4 min read
This new understanding could one day lead to targeted treatments. 
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
Ramified cells in a lilac background
Could Vitamin Supplementation Help Alzheimer’s Patients?
Alejandra Manjarrez, PhD | Apr 11, 2022 | 8 min read
Niacin, a form of vitamin B3 used to treat cardiovascular disease, helps immune cells in the brain fight neurodegenerative diseases such as Alzheimer’s in mice models, according to recent studies. Researchers hope that human clinical trials will swiftly follow.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Rendering of a light blue NLRP3 inflammasome against a black background
Inflammation in Brain’s Immune Cells Triggers Depressive Behavior in Mice
Dan Robitzski | Nov 17, 2022 | 5 min read
In stressful conditions, specialized protein complexes in microglia induce neurotoxic activity in astrocytes that leads to the change in behavior.
Amyloid plaques (stained for amyloid-? peptide) detected in a post-mortem brain sample of a patient with Alzheimer's disease. Purple purple dots in the background are the nuclei of neurons and glia.
Herpes Viruses Implicated in Alzheimer’s Disease
Anna Azvolinsky | Jun 21, 2018 | 5 min read

A new study shows that the brains of Alzheimer’s disease patients have a greater viral load, while another study in mice shows infection leads to amyloid-β build up.

Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Alternative Medicines
The Scientist | Jul 1, 2012 | 10+ min read
As nonconventional medical treatments become increasingly mainstream, we take a look at the science behind some of the most popular.

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