Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.

The Human Genome Project has generated nearly $800 billion in economic output and hundreds of thousands of jobs in genomics and related industries.

Life sciences took center stage virtually around the world June 26. President Bill Clinton, flanked on the left by Celera Genomics Group president J. Craig Venter and on the right by National Human Genome Research Institute director Francis S. Collins, announced the completion of "the first survey of the entire human genome."

The researchers who constructed the first reference genome for this critically endangered mollusk say it will assist restoration efforts.

To successfully use a patient’s genetic makeup in a clinical setting, we must better understand the incredible diversity of human genomes.
 

Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

In Chapter 10, “Deep Discovery,” author Eric Topol considers the marriage of omics and AI.

Nine months have passed since draft sequences of the human genome were first published.1,2 One human gestation period later, the genome, as deciphered by the International Human Genome Sequencing Consortium, still screams toward its projected Spring 2003 finish date. "The trajectory we're on for meeting that goal is precisely on target," assures Francis Collins, director, National Human Genome Research Institute (NHGRI) and spokesperson for the largest public biological science project in histor

The effort to collect samples of DNA from diverse populations strives to overcome alleged public misunderstanding of its aims. SIDEBAR: For More Information MISINTERPRETED: "We need to show that this is just not a group of self-perpetuating insiders," says HGDP committee chairman Ken Weiss. Members of a National Research Council (NRC) panel evaluating the issues-both controversial and prosaic-surrounding the proposed Human Genome Diversity Project (HGDP) have their hands full. Conceived abou