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Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss
A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.
Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss
Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss
A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.
A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.
Alzheimer's Disease, neuroscience, genetics & genomics
Neuroscientist Rahul Desikan Dies
Kerry Grens | Jul 19, 2019 | 2 min read
He developed an MRI-based map of the human cortex, discovered genetic risk factors for neurodegenerative diseases, and wrote about his struggles with ALS.
Alzheimer’s Gene Affects Energy Consumption in Mouse Brains
Sukanya Charuchandra | Oct 1, 2018 | 2 min read
One variant limited the brain’s ability to use glucose.
As the Brain Ages, Glial-Cell Gene Expression Changes Most
Ashley P. Taylor | Jan 10, 2017 | 3 min read
Researchers describe how gene expression in different human brain regions is altered with age.
Week in Review: September 5–9
Jef Akst | Sep 8, 2016 | 2 min read
Environmental magnetite in the human brain; prion structure takes shape; watching E. coli evolve in real time; learning from others’ behavior
Week in Review: May 12–16
Tracy Vence | May 16, 2014 | 3 min read
Antidepressant could prevent Alzheimer’s plaques; 12,000-year-old human skeleton sequenced; disentangling the mystery of octopus arms; taking a look at the ocular microbiome
Week in Review: March 17–21
Tracy Vence | Mar 20, 2014 | 3 min read
Protein appears to protect stressed neurons; vitamin A’s lifelong effects on immunity; stem cells influenced by substrates; supercharged photosynthesis through nanotechnology
New Alzheimer’s-Associated Genes
Tracy Vence | Oct 28, 2013 | 1 min read
A GWAS meta-analysis identifies 11 new loci associated with onset of the neurodegenerative disease.
Natural Alzheimer’s Protection
Sabrina Richards | Jul 11, 2012 | 3 min read
Researchers identify a gene variant that reduces risk of Alzheimer’s disease.
The Genes of Parkinson’s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011 | 10 min read
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.