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tag microbiology disease medicine gene silencing genetics genomics
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
New Strategies to Discover Human Disease Genes
The Scientist
| Oct 16, 2023
| 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa, PhD
| Nov 11, 2022
| 3 min read
A study finds that
XIST
, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males.
Humans Rely on Gut Bacteria for an Enzyme that Prevents Jaundice
Kamal Nahas, PhD
| Feb 16, 2024
| 5 min read
An absence of bilirubin-producing gut microbes may predispose individuals to some diseases, including inflammatory bowel disease.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD
| Dec 4, 2023
| 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Silencing Epigenetic Complexes Re-sensitizes Drug-Resistant Cancer Cells
Rachael Moeller Gorman
| Sep 25, 2023
| 4 min read
Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.
Bacterial Time Capsules May Inform Future Medicines
Danielle Gerhard, PhD
| Nov 1, 2023
| 2 min read
Historical samples of bloodstream infections hold secrets to
Escherichia coli
’s evolutionary history and the emergence of virulent clones.
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD
| Oct 31, 2023
| 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
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