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tag immunology techniques microbiology electron microscopy

An illustration of a flask of bacteria, a weighted microscope slide, and two bacteria exchanging materials via nanotubes.
Infographic: Sources of Variation in Bacterial Nanotube Studies
Sruthi S. Balakrishnan | Jun 1, 2021 | 2 min read
Differences in how researchers prepare and image samples can lead to discrepancies in their results.
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
Suited to a T
Kelly Rae Chi | May 1, 2013 | 8 min read
Sorting out T-cell functional and phenotypic heterogeneity depends on studying single cells.
An artist’s rendering of a DNA-based virus trap, represented as gray rods in a short cone-shaped arrangement. One is coated with blue molecules, likely antibodies, that adhere to a virus target. Another image shows to traps coming together to capture a red coronavirus.
“Origami” DNA Traps Could Keep Large Viruses From Infecting Cells
Natalia Mesa, PhD | Jan 18, 2023 | 4 min read
By engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
A multicolored illustration of a cell undergoing division.
See Beyond the Scatter Plot with Imaging, Spectral Flow Cytometry
The Scientist and BD Biosciences | Aug 9, 2023 | 3 min read
A novel instrument combines fluorescence-activated cell sorting, imaging flow cytometry, and spectral flow cytometry to advance cell population examination.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Articles Alert
Simon Silver | Oct 1, 1990 | 5 min read
Author: SIMON SILVER Department of Microbiology & Immunology University of Illinois Chicago Discovering six new vitamins in a single metabolic pathway is unprecedented, but then, neither methanogenesis nor Ralph Wolfe is standard. The metabolic pathway for converting CO2 to CH2, which is unique to the methanogenic archaebacteria, has shown that there is novel microbiology and metabolic biochemistry work yet to do. A.A. DiMarco, T.A. Bobik, R.S. Wolfe, "Unusual coenzymes of methanogenesis,"
Exosomes Make Their Debut in Plant Research
Amanda Keener | Feb 1, 2019 | 10+ min read
A growing branch of research on how plants use exosomes to interact with their environment is opening up a new field of plant biology.
Articles Alert
Simon Silver | Apr 1, 1990 | 7 min read
Department of Microbiology & Immunology University of Illinois Chicago A surface glycoprotein that is anchored via a lipid to the trypanosome cell membrane is transferred in vitro to red blood cell membranes, sensitizing the latter to attack by anti-trypanosome antibodies. M.R. Rifkin, F.R. Landsberger, "Trypanosome variant surface glycoprotein transfer to target membranes: a model for the pathogenesis of trypanosomiasis," PNAS, 87, 801-5, January 1990. (Rockefeller University, New York)

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