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3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
3D rendered image of multiple antibody-drug conjugate next generation antibodies.
Advances in Antibody Therapeutics
Elina Kadriu | 4 min read
Scientists engineer therapeutic antibodies with improved stability and efficacy. 
Robot hand holding glass sphere with glowing fiber neon communication wires
Gazing into Science’s Crystal Ball
Meenakshi Prabhune, PhD | Mar 15, 2024 | 3 min read
Basic research successes offer glimpses into future scientific advancements, but the outcomes are subject to change.
3D outline of a bone with red dots in the center.
Bringing Immunotherapy Straight to the Source
Aparna Nathan, PhD | Mar 14, 2024 | 4 min read
Engineered natural killer cells track down cancer cells in the bone marrow.
A Spotlight on Cancer Cell Metabolism
A Spotlight on Cancer Cell Metabolism
The Scientist | 1 min read
In this webinar, Elena Piskounova and Christina Towers discuss the implications of metabolic changes in cancer cells for therapeutic development and efficacy. 
3D illustration of a lymphocyte in white and green.
A Quest for the Holy Grail of Cancer Targets
Danielle Gerhard, PhD | Mar 14, 2024 | 5 min read
Christopher Klebanoff hopes that his search for a small fraction of cancer-specific antigens will have a big impact on cancer cell therapies.
3D rendered image showing enhanced scanning electron micrograph of cancer cells.
Turning Off Metastasis in Breast Cancer
Nathan Ni, PhD | Feb 13, 2024 | 4 min read
An on-off enzyme switch controls metastasis in mice. 
How Gut Microbiomes Shape Anti-Tumor Immune Responses
How Gut Microbiomes Shape Anti-Tumor Immune Responses
The Scientist | 1 min read
In this webinar, Andrew Y. Koh will discuss the role of the gut microbiome in modulating cancer immunotherapy. 
Addressing Power and Pitfalls in Machine Learning Neoantigen Prediction
Deanna MacNeil, PhD | Dec 11, 2023 | 4 min read
Researchers honed prediction models and datasets to unlock the potential of deep neural networks in biological applications while avoiding bias.
A microRNA Family Drives the T Cell Response in Cancer
Niki Spahich, PhD | Nov 11, 2023 | 4 min read
When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.
Neoantigen Prediction for Precision Immunotherapies
Neoantigen Prediction for Precision Immunotherapies 
The Scientist | 2 min read
Learn about the tools and resources researchers use to define, discover, and deploy anti-tumor immunotherapies.
Artist’s impression of stem cells. The cells have a transparent cell membrane on a pale blue background.
Overcoming Cancer Therapy Obstacles With Epitope Editing
Rebecca Roberts, PhD | Oct 12, 2023 | 3 min read
Editing epitopes expressed on the surfaces of transplanted hematopoietic stem cells renders them resistant to AML treatments without affecting their critical functions.
SEM
Tuning T Cells
Danielle Gerhard, PhD | Oct 2, 2023 | 2 min read
An often overlooked property of the tumor environment shapes T cell function and may improve T cell therapies.
Sartorius
Understanding the Blood Cancer Genomic Landscape 
The Scientist | 1 min read
Information about the genomic and immunological characteristics of blood cancers is helping scientists discover and develop new immunotherapies.
The Vaginal Microbiome is Finally Getting Recognized
Hannah Thomasy, PhD, Drug Discovery News | Sep 25, 2023 | 10+ min read
Vaginal dysbiosis has long been a taboo subject, but studying and optimizing the vaginal microbiome could be a game changer for women's health.
Scientist pipetting at the bench in white coat and purple gloves
Chek-Mate for Gliomas
Aparna Nathan, PhD | May 22, 2023 | 3 min read
New research may make immunotherapy possible for hard-to-treat brain tumors.
Breaking Down Barriers: Cell Therapy for Solid Tumors
The Persistence of (T Cell) Memory: Towards Cellular Therapy for Solid Tumors
The Scientist | 1 min read
In this webinar, Douglas Green will describe how early events in T cell activation influence anti-tumor immunity. 
Engineered T cells attacking a cancer cell
Helping Engineered T Cells Find Their Way to Tumors
Nele Haelterman, PhD | Apr 18, 2023 | 3 min read
Susan Thomas discusses how her team engineered a microfluidic device to screen for T cells with improved homing capability to tumor cells. 
illustration of T cell attached to protein
“Smarter” CAR T Cells Target Tumors with Precision
Natalia Mesa, PhD | Dec 16, 2022 | 5 min read
Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.
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