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tag techniques cancer microbiology immunology

Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
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How Cellular Heterogeneity Drives Immune Responses
The Scientist Creative Services Team in collaboration with 10x Genomics | Sep 28, 2021 | 2 min read
An expert panel will discuss how single cell multiomic techniques shed new light on immune cell heterogeneity and immune function.
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Jeffrey Perkel | Apr 29, 2001 | 2 min read
Antigen-specific T lymphocytes must be quantified in order to gauge the quality of an immune response. Typically this is accomplished using cytotoxicity assays or limiting dilution analysis (LDA), but these techniques are lengthy and provide indirect quantitation. Also, LDA cannot count nonproliferative cells. In 1996, Stanford University's Mark Davis developed an alternative strategy that overcomes these problems.1 Davis generated phycoerythrin-conjugated tetramers of human lymphocyte antigen (
Pinpointing the Culprit
Rachel Berkowitz | Jun 1, 2017 | 8 min read
Identifying immune cell subsets with CyTOF
Tumor Immunology
The Scientist Staff | Oct 29, 1995 | 3 min read
A.L. Cox, J. Skipper, Y. Chen, R.A. Henderson, T.L. Darrow, J. Shabanowitz, V.H. Engelhard, D.F. Hunt, C.L. Slingluff, "Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines," Science, 264:716-9, 1994. (Cited in more than 60 articles through September 1995) Comments by Victor Engelhard, University of Virginia, Charlottesville The importance of this paper, according to Victor Engelhard, a professor of microbiology at the University of Virginia, is that "
A section of a mouse distal colon showing luminal contents with bacteria in magenta, the mucus lining (green) and the epithelial cell barrier of the gut (blue, right).
Mapping the Neighborhoods of the Gut Microbiome
Abby Olena, PhD | Jul 1, 2022 | 7 min read
Researchers are going beyond fecal samples to understand how the patterns of commensal microbes in the gastrointestinal tract influence development and health.
A stained tissue sample of metastatic pancreatic cancer
Tetanus Immunity Protects Mice Against Pancreatic Cancer
Amanda Heidt | Mar 24, 2022 | 3 min read
Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.

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