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image: Phosphorylation at the Flick of a Switch

Phosphorylation at the Flick of a Switch

By | May 1, 2017

Incorporating light-controlled dimerization domains into kinases provides tight regulation of these enzymes.

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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Deep Pocket Exploration

Deep Pocket Exploration

By | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Synthetic Sensors

Synthetic Sensors

By | December 1, 2016

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

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image: Neural Connectome Method Uses mRNA Barcodes

Neural Connectome Method Uses mRNA Barcodes

By | November 1, 2016

Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.  

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image: How to Track Translation in Living Cells

How to Track Translation in Living Cells

By | October 1, 2016

Four independent research groups develop techniques for visualizing peptide production in living cells.

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image: Promoting Protein Partnerships

Promoting Protein Partnerships

By | September 1, 2016

Scientists generate new protein-protein interactions at an impressive PACE.

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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