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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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image: A New Way to ID Targets of RNA-Binding Proteins

A New Way to ID Targets of RNA-Binding Proteins

By | July 1, 2016

The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.

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image: Sensors for All

Sensors for All

By | May 1, 2016

A versatile modular strategy for detecting small molecules in eukaryotes

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image: Gene Editing Without Foreign DNA

Gene Editing Without Foreign DNA

By | February 1, 2016

Scientists perform plant-genome modifications on crops without using plasmids.

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image: Precision Epigenetics

Precision Epigenetics

By | September 1, 2013

Visualizing specific epigenetic marks at single gene loci is now possible in individual cells.

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image: BRET Meets FRET

BRET Meets FRET

By | May 1, 2013

Scientists create biocompatible, self-luminescing nanoparticles for in vivo imaging.

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image: Timing Turnover

Timing Turnover

By | November 1, 2012

Two-tone fluorescent tags track the movement and life span of proteins within living cells.

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image: Dynamic Delivery

Dynamic Delivery

By | July 1, 2012

Microscopic sponges made entirely of RNA enable efficient gene silencing.

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  1. UC Berkeley Receives CRISPR Patent in Europe
    Daily News UC Berkeley Receives CRISPR Patent in Europe

    The European Patent Office will grant patent rights over the use of CRISPR in all cell types to a University of California team, contrasting with a recent decision in the U.S.

  2. DNA Replication Errors Contribute to Cancer Risk
  3. Should Healthy People Have Their Exomes Sequenced?
    Daily News Should Healthy People Have Their Exomes Sequenced?

    With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

  4. Rethinking a Cancer Drug Target
    Daily News Rethinking a Cancer Drug Target

    The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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