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tag virology techniques gene silencing fluorescent labeling

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Charting a New Course Through the Injured Brain
Rashmi Shivni | Jan 15, 2024 | 4 min read
A state-of-the-art technique helps scientists map out tissue at the single cell level after a demyelinating brain injury.
A Feast of Fluorescence
Deborah Stull | May 13, 2001 | 9 min read
Labeled Nucleotides Complete Labeling Kits Courtesy of BioCrystal Ltd.Cancerous human colon tissue (tumor margins) showing non-transformed cells, which are stained with specifically prepared BioPixels. Not long ago, the options available to scientists for labeling nucleic acids were severely limited. Not only were researchers restricted to working with radioisotopes, but they also had to be satisfied with being able to address only the most basic questions about gene expression and localiz
Next Generation: Fat-Targeted Gene Knockdown
Molly Sharlach | Oct 5, 2014 | 3 min read
A small peptide helps a silencing construct home in on the adipocytes of obese mice.
Beyond Film: Laboratory Imagers
Jorge Cortese | Apr 1, 2002 | 9 min read
Years ago, researchers had only one data-imaging option: autoradiography. These scientists tagged samples—whether nucleic acid, protein, cell, or tissue—with radioactive labels, and captured images on film. Safety concerns, convenience, and sensitivity, spurred the development of alternative techniques, and today, researchers can choose from a range of options, including fluorescence, chemifluorescence, and chemiluminescence, in addition to autoradiography. Fluorescence occurs when
translation gene genetics ribosome enhancers knowable magazine
What Does It Look Like to “Turn On” a Gene?
Alla Katsnelson, Casey Rentz, and Knowable Magazine | May 3, 2019 | 8 min read
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
Kits to Dye For: A Profile of Sequencing Kits for Automated DNA Sequencers
Michael Brush | Nov 9, 1997 | 9 min read
Date: November 10, 1997 Chart 1 In the long series of events inherent in automated DNA sequencing, cranking out DNA labeled with fluorescent tags is, of course, the most important element of a successful procedure. Without properly labeled sequence ladders to analyze, those expensive, automated DNA sequencers have little to do. So to keep them busy, LabConsumer checked out fluorescent automated DNA sequencing kits from eight manufacturers. The kits profiled exploit two methods for labeling se
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Probing Questions
Michael Brush | May 1, 2000 | 7 min read
Nucleic Acid Labeling Kits Nucleic Acid Labeling Kits (continued) Nucleic Acid Labeling Kits (continued) Genisphere's 3DNA™ Expression Array Detection Kit reagents The ability to label nucleic acids with a variety of tagged molecules has led to astonishing advances in molecular biology. Labeled DNA, RNA, and oligonucleotide probes have made possible techniques like the historic Southern blot, the northern blot, and related dot/slot-blotting procedures, in addition to in situ hybridizat
A blood sample containing white and red blood cells.
Enhancing Cell Morphology-Based Analysis
The Scientist and Deepcell | Aug 3, 2023 | 3 min read
Learn how the latest AI-driven technology uses morphology to comprehensively analyze and sort cell populations.

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