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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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image: A New Way to ID Targets of RNA-Binding Proteins

A New Way to ID Targets of RNA-Binding Proteins

By | July 1, 2016

The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.

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image: Sensors for All

Sensors for All

By | May 1, 2016

A versatile modular strategy for detecting small molecules in eukaryotes

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image: Gene Editing Without Foreign DNA

Gene Editing Without Foreign DNA

By | February 1, 2016

Scientists perform plant-genome modifications on crops without using plasmids.

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image: Milling Magic

Milling Magic

By | August 1, 2012

Ion beams carve slices in frozen cells, giving biologists an interior view.

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image: Bubble Vision

Bubble Vision

By | May 1, 2012

Turning a liability into an asset, cryo-electron microscopists exploit an artifact to probe protein structure.

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image: A Brighter Beacon

A Brighter Beacon

By | April 1, 2012

A novel liquid laser set-up can detect single nucleotide mutations in a cancer gene.

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image: Delivering Silence

Delivering Silence

By | March 1, 2012

Using RNA viruses to silence genes could optimize tissue targeting while reducing toxicity.

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