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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Neural Connectome Method Uses mRNA Barcodes

Neural Connectome Method Uses mRNA Barcodes

By | November 1, 2016

Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.  

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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image: A New Way to ID Targets of RNA-Binding Proteins

A New Way to ID Targets of RNA-Binding Proteins

By | July 1, 2016

The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.

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image: Sensors for All

Sensors for All

By | May 1, 2016

A versatile modular strategy for detecting small molecules in eukaryotes

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image: Gene Editing Without Foreign DNA

Gene Editing Without Foreign DNA

By | February 1, 2016

Scientists perform plant-genome modifications on crops without using plasmids.

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image: Practical Proteomes

Practical Proteomes

By | January 1, 2016

Cell type–specific proteomic analyses are now possible from paraffin-embedded tissues.

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image: Holding Neurons Steady

Holding Neurons Steady

By | October 1, 2015

Scientists engineer a feedback loop to fine-tune neuron activity with optogenetics.

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image: Tricky Transfections

Tricky Transfections

By | March 1, 2015

A combination of microinjection and electroporation inserts genes into hard-to-reach cells.

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