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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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image: A New Way to ID Targets of RNA-Binding Proteins

A New Way to ID Targets of RNA-Binding Proteins

By | July 1, 2016

The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.

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image: Sensors for All

Sensors for All

By | May 1, 2016

A versatile modular strategy for detecting small molecules in eukaryotes

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image: Tumor-Shrinking Triple-Helices

Tumor-Shrinking Triple-Helices

By | April 1, 2016

A braided structure and some adhesive hydrogel make therapeutic microRNAs both stable and sticky.

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image: Gene Editing Without Foreign DNA

Gene Editing Without Foreign DNA

By | February 1, 2016

Scientists perform plant-genome modifications on crops without using plasmids.

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image: Bursting Cancer’s Bubble

Bursting Cancer’s Bubble

By | April 1, 2015

Scientists make oxygen-filled microbubbles designed to increase tumor sensitivity to radiation.

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image: Bespoke Cell Jackets

Bespoke Cell Jackets

By | December 1, 2014

Scientists make hydrogel coats for individual cells that can be tailored to specific research questions.

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image: Exit Strategy

Exit Strategy

By | January 1, 2014

Scientists come up with a better way to watch cells leave blood vessels.

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