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image: Practical Proteomes

Practical Proteomes

By | January 1, 2016

Cell type–specific proteomic analyses are now possible from paraffin-embedded tissues.

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image: Holding Neurons Steady

Holding Neurons Steady

By | October 1, 2015

Scientists engineer a feedback loop to fine-tune neuron activity with optogenetics.

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image: Tricky Transfections

Tricky Transfections

By | March 1, 2015

A combination of microinjection and electroporation inserts genes into hard-to-reach cells.

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image: Light-Operated Drugs

Light-Operated Drugs

By | November 1, 2014

Scientists create a photosensitive pharmaceutical to target a glutamate receptor.

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image: Laser-Guided Chastity

Laser-Guided Chastity

By | July 1, 2014

Scientists devise a precision-targeted system for training, tracking, and tweaking fruit fly social behavior.

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image: Fuel Gauge

Fuel Gauge

By | May 1, 2014

An optical reporter quantitatively measures the ATP demands of presynaptic neurons.

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image: Flickering Neurons

Flickering Neurons

By | February 1, 2013

Fluorescent calcium sensors in transgenic mice give a real-time readout of neuronal activity.

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image: Milling Magic

Milling Magic

By | August 1, 2012

Ion beams carve slices in frozen cells, giving biologists an interior view.

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image: Bubble Vision

Bubble Vision

By | May 1, 2012

Turning a liability into an asset, cryo-electron microscopists exploit an artifact to probe protein structure.

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image: Deep Tissue Treatment

Deep Tissue Treatment

By | September 1, 2011

A new, genetically encoded tag for electron microscopy may revolutionize studies of specific proteins in cells and tissues.

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