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Jeffrey Perkel | Apr 29, 2001 | 2 min read
Antigen-specific T lymphocytes must be quantified in order to gauge the quality of an immune response. Typically this is accomplished using cytotoxicity assays or limiting dilution analysis (LDA), but these techniques are lengthy and provide indirect quantitation. Also, LDA cannot count nonproliferative cells. In 1996, Stanford University's Mark Davis developed an alternative strategy that overcomes these problems.1 Davis generated phycoerythrin-conjugated tetramers of human lymphocyte antigen (
Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Top Ten Innovations 2011
The Scientist | Jan 1, 2012 | 10+ min read
Our list of the best and brightest products that 2011 had to offer the life scientist
Refinements In Bioluminescence Assays Expand Technique's Applications
Ricki Lewis | Mar 6, 1994 | 8 min read
The following vendors develop and/or market bioluminescence assay kits, products, and instrumentation for a variety of research and clinical laboratory uses. For more information about products, services, and prices, please contact these companies directly. Accurate Chemical and Scientific Corp. 300 Shames Dr. Westbury, N.Y. 11590 (800) 645-6264 - Fax: (516) 997-4948 Analytical Luminescence Laboratory 11760 Sorrento Valley Rd., S
Refinements In Bioluminescence Assays Expand Technique's Applications
Ricki Lewis | Mar 6, 1994 | 8 min read
The following vendors develop and/or market bioluminescence assay kits, products, and instrumentation for a variety of research and clinical laboratory uses. For more information about products, services, and prices, please contact these companies directly. Accurate Chemical and Scientific Corp. 300 Shames Dr. Westbury, N.Y. 11590 (800) 645-6264 - Fax: (516) 997-4948 Analytical Luminescence Laboratory 11760 Sorrento Valley Rd., S
Suited to a T
Kelly Rae Chi | May 1, 2013 | 8 min read
Sorting out T-cell functional and phenotypic heterogeneity depends on studying single cells.
Sons of Next Gen
Tia Ghose | Jun 1, 2012 | 8 min read
New innovations could bring tailored, fast, and cheap sequencing to the masses.
No Mo’ Slow Flow
Jeffrey M. Perkel | Jan 1, 2012 | 7 min read
Tools and tricks for high-throughput flow cytometry

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