neuroscience, methods

Two-photon imaging captures chemical signaling between live mouse neurons on a millisecond timescale.

Researchers flipped light-sensitive proteins upside down for a new twist on optogenetics.

Ultraflexible mesh electrodes monitor the intact, functioning eyes of awake animals.

Mini-brains can be grown in culture or printed.

Researchers identified thousands of immature neurons in the brain region, countering a recent result showing little, if any, signs of neurogenesis.

Researchers develop a new technique to selectively activate neurons deep in the rodent brain, taking a step toward noninvasive brain stimulation for neurological disorders.

A decades-old neurological procedure developed under unique and difficult conditions in postwar Japan remains critical to the treatment of epilepsy.

Micrometer-size magnetrodes detect activity-generated magnetic fields within living brains.

Newly designed sensors detect the magnetic fields generated by electrical activity within cat brains.

Two groups of scientists combined automation with two-photon microscopy to target and record specific neurons in living animals. 

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

Current can guide implanted cells away from rats’ noses toward a region deep in their brains.

A heat block, a truck battery, and a novel RNA amplification assay make for in-the-field surveillance of the virus.

A double-expansion technique embeds brain tissue in the absorbent material of diapers to stretch out cells for easier visualization.

Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.
 

Barcodes of mRNA travel to the cells' axon terminals, offering a sequencing-based approach to neural mapping.

Credit for the neuroscience technique has largely overlooked the researcher who first demonstrated the method.

“Ultimate DISCO” uses a solvent that shrinks whole animals and preserves fluorescence for months.

Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

Cell type–specific proteomic analyses are now possible from paraffin-embedded tissues.