Aileen Constans | Apr 14, 2002 | 3 min read
Most of the attention on gene expression analysis and discovery tools has centered on microarray technology, but alternative methods, including SAGE (serial analysis of gene expression)1 and direct cDNA sequencing, do exist. Another such technique is Hayward, Calif.-based Lynx Therapeutics' Massively Parallel Signature Sequencing (MPSS™) technology, a method for counting millions of mRNA molecules from a given sample. Like SAGE, MPSS quantifies tagged cDNA fragments; but whereas SAGE uses