Jill Adams | Oct 10, 2004 | 6 min read
LIPID RAFTS INSIDE AND OUT:© 2002 AAASIn the outer leaflet (A), sphingolipids and cholesterol form less fluid microdomains (B) called lipid rafts, which are enriched for GPI-proteins. Microdomains may contain more rigid subdomains (C) enriched for the sphingolipid ganglioside GM1. The membrane inner leaflet contains microdomains (D) with unknown lipid composition enriched for prenylated proteins. In contrast, caveolin and proteins carrying the two saturated fatty acyl chains become concentr