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tag disease medicine cell molecular biology evolution history biodiversity

The structure of a biological cell (macro)
The Long and Winding Road to Eukaryotic Cells
Amanda Heidt | Oct 17, 2022 | 10+ min read
Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
The Devolution of Evolution
Leonid Moroz | Nov 1, 2010 | 4 min read
By Leonid Moroz The Devolution of Evolution Why evolution and biosystematics courses must be included in all biomedical curricula. Nearly 40 years ago Theodosius Dobzhansky wrote: “Nothing in biology makes sense except in the light of evolution.” How is it, then, that so few newly minted PhDs in the biological sciences have taken any formal graduate school courses in evolution or biodiversity? This fosters a knowledge gap that can become difficult t
Plague Genome: The Evolution Of a Pathogen
Ricki Lewis | Oct 28, 2001 | 7 min read
Plague has earned a place in history books as the Black Death of medieval Europe, and in novels, from Albert Camus' classic The Plague, to the more recent Year of Wonders.1,2 A different medium for telling the tale of the plague bacterium Yersinia pestis is its genome, recently sequenced by researchers at the Sanger Centre, the London School of Hygiene and Tropical Medicine, the Royal London School of Medicine and Dentistry, and the Imperial College of Science, Technology and Medicine.3 In addi
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Genetic Variation Illuminates Murky Human History
Douglas Steinberg | Jul 23, 2000 | 8 min read
If humans are 99.9 percent genetically identical, as President Bill Clinton is fond of asserting when he extols the Human Genome Project, that 10th-of-a-percent difference has a lot of explaining to do. How does genetic variation determine a person's unique physical traits? Can it predict someone's susceptibility to a disease? Such questions, pertaining to the present or future, are what occupy most human geneticists. A small group, however, studies genetic variation as a clue to the past. Som
Evolution, Resisted
Elie Dolgin | Oct 1, 2009 | 10+ min read
Scientists are trying to design the last malaria control agent the world will ever need.

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