Insulin, long recognized as a primary regulator of blood glucose, is now also understood to play key roles in neuroplasticity, neuromodulation, and neurotrophism.
Advertisement
Infographics
Most Recent
Gene therapies typically involve the introduction of genetic material into target cells to replace or supplement an existing, usually dysfunctional, gene. Techniques for delivering the corrective payload vary widely. Many gene therapies utilize modif
A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve
The Pediatric Research Equity Act (PREA) of 2003 requires that companies developing new drugs that could be used to treat a condition in children perform clinical trials in kids before winning FDA approval. The Best Pharmaceuticals for Children Act (
Normal pancreatic function depends on the precise flow of calcium within and into the acinar cells of the organ. When food is eaten, low concentrations of the pancreas-stimulating hormone cholecystokinin or of the neurotransmitter acetylcholine cause
Not all inflammation leads to pain. Despite widespread infection followed by fever, colds rarely cause pain. But when some cytokines and certain immune cells are active near pain-sensing nerves, they trigger receptors that convey pain sensations to t
Looking for a more realistic way to study memory, we turned to place cells—a network of cells that record a rat’s memory of an environment. Each place cell would fire only when the rat was in one particular location in space, creating a map as the
Long-term potentiation (LTP), discovered in the 1970s, was later shown to be the molecular basis of memory. Since many diseases of aging affect memory, could memory formation and storage be altered by the same mechanisms in normal aging and diseased
Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to t
The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—from traumatic brain injury, to epilepsy, infection, or genetic predisposition—can activate brain immune cells—
Follow The Scientist
Stay Connected with The Scientist
-
The Scientist Magazine
-
The Scientist Careers
-
Neuroscience Research Techniques
-
Genetic Research Techniques
-
Cell Culture Techniques
-
Microbiology and Immunology
-
Cancer Research and Technology
Current Issue
