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tag immunology physiology biochemistry inflammation techniques

T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
3D image of a neuron cell network with a red glow representing inflammation.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Immune to Failure
Karen Hopkin | Feb 1, 2013 | 9 min read
With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.
bertozzi
Carolyn Bertozzi: Glycan Chemist
Anna Azvolinsky | Jun 1, 2016 | 9 min read
Bertozzi opens visual windows onto complex sugars on and inside living cells.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Ultimate Abs
Deborah Wilkinson | Apr 16, 2000 | 10+ min read
Antibody Purification Reagents The immune response is often exploited to produce those remarkably useful affinity reagents known as antibodies. Today's biological and biomedical laboratories employ an array of different immunochemical techniques. For example, a specific antibody can be harnessed to screen for the presence of its respective antigen, quantify the amount of antigen in a given sample, determine the antigen's subcellular location, isolate the antigen from complex mixtures, and sear
Enter the Matrix
Ricki Lewis | Apr 25, 2004 | 6 min read
WHAT A TANGLED WEB:Courtesy of Philip B. MessersmithFibroblasts are cellular workhorses of extracellular matrix production, spinning out the majority of collagens, the most abundant proteins in the animal kingdom.Appreciation in biology can come slowly. Researchers once deemed as junk the parts of genes not represented in proteins; likewise, neuroglia were thought to be mere bystanders to neurons. So it is with the extracellular matrix (ECM), the "scaffolding" and "glue" that fill the spaces amo
Assays by the Score
Deborah Fitzgerald | May 27, 2001 | 9 min read
Click to view the PDF file: Bead-based Fluorescent Multiplex Protein Analysis Systems Courtesy of LINCO ResearchLabMAP-based systems use internally dyed fluorescent microspheres to analyze as many as 100 different analytes concurrently. Today's competitive, high-paced research environment has stimulated the development of a host of approaches for rapid, cost-efficient analyses of large numbers of samples. In keeping with this trend, methods for simultaneously analyzing multiple species in a g
Notebook
The Scientist Staff | Mar 15, 1998 | 7 min read
POWER EXCHANGE: Molecular biologist James Battey has become the second person to head NIDCD. SECOND GENERATION AT NIDCD Molecular biologist James F. Battey, 45, has been named the new director of the National Institute on Deafness and Other Communication Disorders (NIDCD) of the National Institutes of Health. Battey, who had been serving as acting director of NIDCD, succeeds the recently retired James B. Snow, Jr. Snow, a former University of Pennsylvania professor of otorhinolaryngology and h

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