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image: Mind the Clock

Mind the Clock

By | September 1, 2013

Many of the body's tissues can tell time, and these peripheral clocks can be influenced by environmental cues, such as the timing of food consumption.

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image: Antibody-Dependent Enhanced (ADE) Immunity

Antibody-Dependent Enhanced (ADE) Immunity

By | March 2, 2013

The method to the dengue virus's maddening infectiousness.

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image: Rhinoviruses Exposed

Rhinoviruses Exposed

By | February 1, 2013

Some of these insidious viruses expertly subvert the host immune system, allowing their unhindered proliferation.

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image: Adipose Tissue Metabolism in the Obese

Adipose Tissue Metabolism in the Obese

By | December 12, 2012

Fat cells behave differently in obese individuals, causing inflammation and insulin resitance.

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image: Normal Fat Tissue Metabolism

Normal Fat Tissue Metabolism

By | December 6, 2012

Adipose tissue plays an immune role in individuals of normal wieght.

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image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role

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image: Ubiquitin basics

Ubiquitin basics

By | July 1, 2012

Despite its discovery as a protein that seems to show up everywhere, at least in eukaryotic cells, researchers are only beginning to scratch the surface of all of the cellular functions involving ubiquitin. 

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image: Delivering New Genes

Delivering New Genes

By | June 1, 2012

Gene therapies typically involve the introduction of genetic material into target cells to replace or supplement an existing, usually dysfunctional, gene. 

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image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 

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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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