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tag physiology drug development neurodegeneration metabolism

Keeping Kidneys Healthy with a Hand from AI
Aparna Nathan, PhD | Dec 11, 2023 | 3 min read
Researchers found new mechanisms and drug targets for cystinosis.
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
How Exercise Reprograms the Brain
Ashley Yeager | Nov 1, 2018 | 10 min read
As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.
Tuning the Brain
Andres Lozano | Oct 28, 2013 | 10 min read
Deep-brain stimulation is allowing neurosurgeons to adjust the neural activity in specific brain regions to treat thousands of patients with myriad neurological disorders.
Bespoke Stem Cells for Brain Disease
Nsikan Akpan | Jan 14, 2013 | 3 min read
Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.
Secrets of Aging
Carol Barnes | Sep 1, 2011 | 10+ min read
What does a normally aging brain look like? Are diseases of aging such as Alzheimer’s inevitable?
Power Failure
Megan Scudellari | May 1, 2011 | 10+ min read
Does mitochondrial dysfunction lie at the heart of common, complex diseases like cancer and autism?
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.

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