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image: How High Fat and Insulin Levels May Lead to Diabetes

How High Fat and Insulin Levels May Lead to Diabetes

By | July 1, 2016

Lipids and insulin play important roles in blood sugar regulation, and altered levels of either could kick start metabolic dysfunction.

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image: Going Viral

Going Viral

By | September 1, 2013

Bacteriophages shuttle genes between diverse ecosystems.

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image: Networking Medicine

Networking Medicine

By | March 2, 2013

Although fully organized patient-run trials are still few and far between, patients are taking a more active role in clinical research.

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image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role

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image: Ubiquitin basics

Ubiquitin basics

By | July 1, 2012

Despite its discovery as a protein that seems to show up everywhere, at least in eukaryotic cells, researchers are only beginning to scratch the surface of all of the cellular functions involving ubiquitin. 

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image: Delivering New Genes

Delivering New Genes

By | June 1, 2012

Gene therapies typically involve the introduction of genetic material into target cells to replace or supplement an existing, usually dysfunctional, gene. 

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image: Digging the Underground Life

Digging the Underground Life

By | June 1, 2012

A rare peek inside the subterranean home of the naked mole-rat

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image: Messing with HIV

Messing with HIV

By | June 1, 2012

Sangamo Biosciences is putting a different spin on gene therapy. 

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image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 

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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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