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tag biochemistry drug development physiology cancer

Lasker Award winner Piet Borst sits at his desk.
A Journey With Metabolism, Parasites, and Cancer
Laura Tran, PhD | Sep 21, 2023 | 7 min read
Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Developing Aptamer Biosensor Technology for Diagnostics and Therapeutics
Expanding the Available Target Range for New Drugs and Diagnostics with Aptamers
The Scientist and aptamer Group | May 3, 2022 | 1 min read
In this roundtable discussion, an expert panel will discuss how the latest applications of aptamer technology are enabling innovation across the life sciences by replacing antibodies.
Rethinking Lymphatic Development
Amanda B. Keener | Aug 1, 2015 | 9 min read
Four studies identify alternative origins for cells of the developing lymphatic system, challenging the long-standing view that they all come from veins.
Freezing Time
Vern L. Schramm | May 1, 2012 | 10+ min read
Targeting the briefest moment in chemistry may lead to an exceptionally strong new class of drugs.
Contributors
Catherine Offord | Apr 1, 2016 | 3 min read
Meet some of the people featured in the April 2016 issue of The Scientist.
Luminescence Developments Help Scientists See The Light
James Kling | May 11, 1997 | 9 min read
Biologists are constantly seeking more sensitive assays to detect the presence of organisms or telltale DNA, RNA, and proteins. Although radioactive tags incorporated into the target itself (or into a complementary strand)-and later detected by Geiger counters or film exposures-have traditionally given good sensitivity, the problems of waste disposal and laboratory monitoring have driven a search for alternative tags that have radioactivity's sensitivity but avoid its hazards. Fluorescent tags-
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Defined Primary Cell Culture and Media
The Scientist Creative Services Team in collaboration with MilliporeSigma | Jul 29, 2021 | 3 min read
A new partnership opens the door for a source of highly purified human primary cells and defined cell culture media.

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